Breast Support Formula

1. NLRP3

a. https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2615-4

b. Inhibits tumor growth and metastasis in TNBC

2. Caspase-9 mediated apoptosis

a. https://www.sciencedirect.com/science/article/abs/pii/S0753332217323235

b. Inhibits cell growth and promotes apoptosis in TNBC

c.

3. Decreases cyclin A and CDK1

a. https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.28628

b.

4. Cell cycle arrest and induces apoptosis

a. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036777/

5. Downregulation of TGF-B1

a. https://www.karger.com/Article/Fulltext/487171

1. Epigenetic reprogramming in TNBC

a. https://www.sciencedirect.com/science/article/pii/S2352340917300252

b.

2. Cell cycle arrest and antiangiogenesis

a. https://www.hindawi.com/journals/jo/2016/9750785/

b.

3. Mediates apoptosis through reduction in POLD 1 expression

a. https://www.frontiersin.org/articles/10.3389/fonc.2021.569295/full

b.

4. Immunoregulatory effects increasing il-2 and IFN -y downregulating PD-1

a. https://www.sciencedirect.com/science/article/abs/pii/S0008874921001428